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May 06, 2026
 

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STEM CELLS

A Japanese research team has developed miniaturized testicular tissues called testicular organoids from mouse embryonic stem cells, in a world first.
JAPAN / Science & Health
Feb 27, 2026
Japanese researchers create mouse testicular organoids in vitro
Two of the researchers were also the first to create ovarian organoids from mouse embryonic stem cells, in 2021.
An iPS cell-derived heart muscle sheet developed by Cuorips
JAPAN / Science & Health / FOCUS
Feb 20, 2026
iPS cell-based products win conditional approval from health ministry panel
The endorsement was based on small-scale clinical studies that confirmed only their safety and ¡°presumed¡± their efficacy.
Myocardial sheets made from iPS cells
JAPAN
Feb 19, 2026
Japan panel OKs medical products using iPS cells
The products, if approved by the health minister, are expected to be the world's first of their kind.
A clinical trial by a Tokyo-based venture company has confirmed that transplanting cardiac muscle cell clusters created from iPS cells into patients with severe heart failure improved their cardiac functions and symptoms.
JAPAN / Science & Health
Dec 13, 2025
Tokyo startup confirms efficacy of iPS cell-derived heart muscle transplants
According to Friday's announcement, the transplant was performed on 10 patients, and no major safety issues were confirmed.
With concerns rising over babies whose genetic makeup has been altered to accommodate the parents' preferences, the government aims to submit related legislation during next year's ordinary parliamentary session at the earliest.
JAPAN
Dec 4, 2025
Japan eyes ban on gene-edited babies
The government aims to submit related legislation during next year's ordinary parliamentary session at the earliest.
A Japanese research team comprising researchers from Kyoto University's Center for iPS Cell Research and Application and other institutions succeeded in producing iPS cells by adding artificially synthesized ribonucleic acid to human blood cells.
JAPAN / Science & Health
Dec 4, 2025
Japan team develops effective method to create iPS cells from blood
While a method to create iPS cells using skin cells and synthetic RNA has already been developed, it had been thought to be difficult to produce iPS cells from blood cells.
A research team from Kyoto University has announced that it is the first in the world to create 3D jawbone-like organoids from human induced pluripotent stem, or iPS, cells.
JAPAN / Science & Health
Aug 19, 2025
Kyoto University group successfully creates jawbone from iPS cells
The team expects that its method will be applied to regenerative medicine and drug discovery.
Sumitomo Pharma applied to Japanese regulators for manufacturing and marketing authorization aimed at treating patients with advanced Parkinson's disease.
JAPAN / Science & Health
Aug 5, 2025
Drugmaker in Japan seeks approval for stem cell treatment for Parkinson's
A trial led by Kyoto University researchers indicated treatment using induced Pluripotent Stem cells was safe and successful in improving symptoms of the disease.
A regenerative medicine startup, Kyoto-based iHeart Japan, said Monday that it has conducted a clinical trial to transplant a treatment sheet containing cardiac muscle cells derived from human induced pluripotent stem cells into a patient with a heart muscle disease.
JAPAN / Science & Health
Jul 29, 2025
Japan startup transplants iPS cells for heart treatment in clinical trial
The layered sheet containing three types of cells and gelatin particles were placed on the surface of the heart, and are expected to improve the heart's contractions.
A screenshot of a health ministry website shows an application form to submit documents for approval of a regenerative medicine program.
JAPAN / Science & Health
Jul 28, 2025
Health bureaus' inconsistencies on regenerative medicine plans spark outcry
In one case, a regional health and welfare bureau immediately approved a regenerative medicine program but a different bureau rejected the same treatment plan.
By pioneering stem cell therapies, Japan is not only treating disease but also seeking to rejuvenate a nation grappling with aging and decline.
COMMENTARY / Japan
Jun 20, 2025
Japan is helping lead the way in regenerative medicine
In pristine labs across Japan, scientists are tinkering with the architecture of regeneration.
A Japanese team has started a final-stage clinical trial to administer to patients with familial Alzheimer's disease a drug discovered using iPS cells.
JAPAN / Science & Health
Jun 4, 2025
Japanese team starts final-stage trial for iPS drug to treat Alzheimer's
Through the trial, which began in May, the team aims to confirm the safety and efficacy of the treatment, with hopes of obtaining regulatory approval.
Kyoto University's Center for iPS Cell Research and Application in Kyoto
JAPAN / Science & Health
Apr 23, 2025
Japan team treats chronic kidney disease with iPS cells in mice
The hope is such an achievement leads to the development of an effective therapy for chronic kidney disease.
A 3D rendering of multiple induced pluripotent stem cells
JAPAN
Apr 18, 2025
University of Osaka team develops miniature livers from iPS cells
The team expects the small livers can be used to treat patients with end-stage liver disease.
Parkinson's disease is a neurodegenerative condition in which motor function is impaired due to a decrease in nerve cells that produce dopamine, a chemical that works in the brain.
JAPAN / Science & Health
Apr 17, 2025
Japan succeeds in improving Parkinson's symptoms with iPS cells
A trial saw nerve cells made from iPS cells transplanted into patients' brains.
It is the first transplant surgery in the hospital's clinical trial for treating Type 1 diabetes through the transplantation of pancreatic cell sheets made from iPS cells.
JAPAN
Apr 15, 2025
Kyoto hospital succeeds in iPS sheet transplant to diabetic patient
It is the first clinical application of such sheets in Japan.
Keio University in Tokyo
JAPAN / Science & Health
Mar 22, 2025
Keio University team says stem cell treatment helped improve spine injuries
Keio University said that the motor function score for two patients improved after an operation to implant more than 2 million iPS-derived cells into a spinal cord.
The health ministry issued a business improvement order to a medical clinic in Fukuoka, saying a range of stem cell treatments it offers violate the law on the safety of regenerative medicine.
JAPAN / Science & Health
Mar 5, 2025
Fukuoka clinic issued business improvement order over stem cell treatments
The clinic offers various stem cell treatments without the prior submission of its plans to the authorities, the health ministry said.
Kyoto University's CiRA Foundation will automatically make autologous induced pluripotent stem cells and turn them into heart muscle and nerve cells at a new facility in the city of Osaka starting in April.
JAPAN / Science & Health
Jan 8, 2025
Automated iPS cell production to start in Japan in April
Autologous iPS cells will be created and turned into, among others, heart muscle and nerve cells.
A colony of human induced pluripotent stem (iPS) cells established from fibroblasts. Kyoto University Hospital is looking to develop a treatment for Type 1 diabetes using iPS cells.
JAPAN / Science & Health
Sep 3, 2024
Kyoto University Hospital seeks to treat Type 1 diabetes using iPS cells
Researchers will begin clinical trial of a treatment as early as next year, which they hope will become available in the 2030s.
China's rare defiance of U.S. sanctions sparks showdown over banks
A Chinese flag flutters in front of the Shanghai Gaoqiao Company Refinery in Shanghai.
Strong winds disrupt transport during Golden Week
A map on the website of the Japan Meteorological Agency shows advisories and warnings for strong winds across wide areas of Japan through Monday night.
Bankruptcies among Japan¡¯s medical, nursing care providers surge to highest in decades
The surge in bankruptcies among medical and nursing care operators is mostly attributed to staff shortages and rising costs.
One Japanese aboard cruise ship hit by hantavirus outbreak
The cruise ship MV Hondius anchored off the port of Praia, the capital of Cape Verde, on Monday
Water shortages hit tourist spots in Japan during Golden Week
A hot spring facility in the city of Tomioka, Gunma Prefecture, has suspended the operation of its open-air baths since March.
Fujisawa flashpoint: A mosque project stokes nativist fears
Muslims pray at Tokyo Camii in the Yoyogi-Uehara neighborhood. Though Muslims account for only 0.3% of Japan¡¯s population, rhetoric in online spaces and by conservative politicians has fomented social tensions.
As Iran war sends oil prices soaring, some see fresh potential for solar in Japan
An agrivoltaic crop, in which solar panels are raised about 3 meters off the ground so that agricultural machinery can freely operate on the crops underneath, in Sosa, Chiba Prefecture.
No longer shushed: Japan¡¯s cultural venues make room for children
In 2019, Saitama Arts Theater started permitting children under 3 to some of its shows. Previously, children under 4 were not permitted.
New head chef at Maz explores Peruvian food through a Japanese lens
Since taking over Maz last month, chef Yuya Nakamura has been gradually introducing more Japanese influences to the restaurant's innovative Peruvian cuisine.
For tourists in Japan¡¯s outdoor sports scene, safety is not guaranteed
Each winter, countless tourists flock to Japan's famous snow-covered mountains, but a lack of top-down regulation on the country's outdoor sports industry can make certain activities unnecessarily risky.

Podcast

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Longform

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